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Lisa Mathew, M.D.
in Denver

About Lisa Mathew M.D.

Dr. Mathew attended the University of Dayton for her undergraduate studies and went on to Duke Medical School for her medical training.  While there, she also completed a Masters of Public Health program at the University of North Carolina. She then moved to Philadelphia to complete her internship and residency in internal medicine at the Hospital of the University of Pennsylvania.  Subsequently, she continued her training as a gastroenterology and Hepatology Fellow at the University of Washington in Seattle. She joined South Denver Gastroenterology in 2014. 

Outside of work, Dr. Mathew enjoys spending her time hiking, skiing, biking and spending time with her husband and three children.  She’s a terrible chef, but enjoys food greatly.

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Patient Care Philosophy

I strive to develop a collaborative, patient-centered approach to care. By focusing on evidence-based diagnostic and therapeutic interventions, I work closely with local internists, surgeons and other providers to deliver the highest quality of care.

Clinical Expertise

Colonoscopy screening and colorectal (colon) cancer prevention
Inflammatory bowel diseases
Esophageal disorders
Gastroesophageal reflux disease (GERD) 
Clinical nutrition


Duke University School of Medicine, MD
University of North Carolina, School of Public Health, Master’s of Science in Public Health
Hospital of the University of Pennsylvania, Internship and Residency, Internal Medicine
University of Washington, Fellowship, Gastroenterology

Board Certifications and Societies

American Board of Internal Medicine
American Board of Internal Medicine/Gastroenterology

Associations and Memberships

American Gastroenterological Association

Dr Mathew was a great listener and really was caring to what I was going through. I would recommend her to anyone.

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Dr. Mathew is always attentive and  helpful. 

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Dr. Mathew is very compassionate and caring. Her knowledge is reassuring.

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South Denver GI Locations

Castle Rock Clinic

3911 Ambrosia St. #201 Castle Rock, CO 80109

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P: 303.788.8888
F: 303.660.6607

Castle Rock Endoscopy Center

3911 Ambrosia St. #200 Castle Rock, CO 80109

Get Directions
P: 303.788.8888
F: 303-660-3996