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Lisa Mathew, M.D.

About Lisa Mathew M.D.

Dr. Mathew attended the University of Dayton for her undergraduate studies and went on to Duke Medical School for her medical training.  While there, she also completed a Masters of Public Health program at the University of North Carolina. She then moved to Philadelphia to complete her internship and residency in internal medicine at the Hospital of the University of Pennsylvania.  Subsequently, she continued her training as a gastroenterology and Hepatology Fellow at the University of Washington in Seattle. She joined South Denver Gastroenterology in 2014. 

Outside of work, Dr. Mathew enjoys spending her time hiking, skiing, biking and spending time with her husband and three children.  She’s a terrible chef, but enjoys food greatly.

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Patient Care Philosophy

I strive to develop a collaborative, patient-centered approach to care. By focusing on evidence-based diagnostic and therapeutic interventions, I work closely with local internists, surgeons and other providers to deliver the highest quality of care.

Clinical Expertise

Colonoscopy screening and colorectal (colon) cancer prevention
Inflammatory bowel diseases
Esophageal disorders
Clinical nutrition


Duke University School of Medicine, MD
University of North Carolina, School of Public Health, Master’s of Science in Public Health
Hospital of the University of Pennsylvania, Internship and Residency, Internal Medicine
University of Washington, Fellowship, Gastroenterology

Board Certifications and Societies

American Board of Internal Medicine
American Board of Internal Medicine/Gastroenterology

Associations and Memberships

American Gastroenterological Association

Me, being in my sixties and quite healthy, I don't have much experience with doctors or medical procedures. Dr. Mathew and her staff were very professional, courteous, insightful and personable. This was my first colonoscopy and a very good experience. Thank you!

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My husband and I can't say enough good things about Dr. Lisa Mathew! She's knowledgeable and professional but very personable which really helped put my husband's mind at ease before his "upper scope." She is just fantastic!

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Dr. Mathew is very professional and made the whole experience more comfortable with all concerns and questions answered. To add, her kind and caring demeanor put anxiety to rest. I highly recommend her practice as all her staff is GREAT!

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South Denver GI Locations

Castle Rock Clinic

3911 Ambrosia St. #201 Castle Rock, CO 80109

Get Directions
P: 303.788.8888
F: 303.660.6607

Castle Rock Endoscopy Center

3911 Ambrosia St. #200 Castle Rock, CO 80109

Get Directions
P: 303.788.8888
F: 303-660-3996